No one can stay young forever. But calorie restriction occurs to be one of the most promising strategy to slow down the process of aging and to support health. It activates enzymes, especially sirtuin 1, associated with energy metabolism, stress resistance, cell survival, and longevity.

That’s why the Vital Solutions' R&D team searched for natural ingredients that imitate the effect of calorie restriction without lowering food intake.

The innovation is: Careless - an exclusive mango fruit preparation, Mangifera indica (L.), which mimics calorie restriction. It helps you to care less about metabolism and aging while delivering the great taste and pleasure of exotic mango fruits.

Careless was divided into two products, Care300 and Careflow, based on applications.

Care300 - activities key metabolic master switch enzymes, AMPK and SIRT1, which regulate energy homeostasis and thereby stimulate metabolism, glucose tolerance, and endothelial function, while delivering the great taste and pleasure of exotic mango fruits.

Care300 guarantees highest, consistent and defined quality. It is scientifically proven, IP protected, and frequently used in food supplements.

Care300® helps to support:*

  • Metabolism
  • Glucose tolerance
  • Endothelial function

Human study results confirm:

Care300 is able to support metabolism and glucose tolerance. In an animal study as well as in a long term double blind, randomized, placebo-controlled, parallel design human study with 75 healthy people, 300 mg Care300 were administered once a day. Results demonstrated that Care300 is able to support metabolism, glucose tolerance and endothelial function.


Appearance: Fine yellow powder with characteristic odor
Loss on drying: < 5.0 %
Solubility Not soluble in water, dispersible in water
Particle size: > 95 % < 160 µm
Bulk density: 0.4 - 0.6 g/ml
Tapped density: 0.5 - 0.7 g/ml
Mangiferin ≥ 0.03%
pH 3.1 - 4.8 10 % water solution
Foreign matter not detected
Pesticides (EC) No 396/2005: complies
Heavy metals (EC) No 1881/2006: complies
Microbiology: Ph. Eur. 7ed Cat. 5.1.4 complies


Care300® - Science & Application

Care300, the proprietary Mangifera indica fruit preparation, is a 100% pure mango fruit powder – validated for efficacy.

In vitro, animal and human studies demonstrated that Careless activates key metabolic master switch enzymes, AMPK and SIRT1, which regulate energy homeostasis, and thereby stimulates metabolism, glucose tolerance, and endothelial function.

Care300 is a high quality, sustainable, IP protected, natural ingredient, approved to be used in food supplements, foods and beverages. It is a water dispersible fine beige powder with a fruity taste. Its recommended daily dosage is 300 mg.

Care300® - Origin & Production

Care300 is a 100% pure mango fruit powder, obtained from a variety called Kili-mookku”. The carefully selected fruits are organically cultivated in the South of India in the Tamil Nadu region and harvested at the special degree of ripeness, when the content of secondary plant ingredients is high and sugar is low. Eating fresh ripe mangoes may not provide the same health effects.

Vital Solutions' research and extensive know-how in natural products enabled them to identify this special subspecies supporting healthy metabolic aging.

Care300’s modern, state of the art, and GMP compliant production facility ensures reproducible quality of the product. All processing steps are organic certified. Care300 complies with highest quality and traceability standards, completed by phytochemical characterization and stability data. Care300 is made in Germany.



Care300® supports concepts for:*


Metabolic health
- to improve glucose tolerance

Body composition
- to maintain a healthy body composition


* These statements have not been evaluated by FDA and EFSA. The product is not intended to diagnose, treat or cure any disease.